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Did you mean cold and salivary gland (260 results)?
Recent Advances on Immunohistochemistry and Molecular Biology for the Diagnosis of Adnexal Sweat Gland Tumors.
Macagno N, Sohier P, Kervarrec T, Pissaloux D, Jullie ML, Cribier B, Battistella M. Macagno N, et al. Cancers (Basel). 2022 Jan 18;14(3):476. doi: 10.3390/cancers14030476. Cancers (Basel). 2022. PMID: 35158743 Free PMC article. Review.
Cutaneous sweat gland tumors are a subset of adnexal neoplasms that derive or differentiate into the sweat apparatus. ...Most of these molecular alterations are represented by gene fusions, which are shared with other homologous neoplasms occurring in organs containing exo …
Cutaneous sweat gland tumors are a subset of adnexal neoplasms that derive or differentiate into the sweat apparatus. ...Most of thes …
CYLD Cutaneous Syndrome.
Dubois A, Rajan N. Dubois A, et al. 2020 Apr 16. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2020 Apr 16. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 32298062 Free Books & Documents. Review.
CLINICAL CHARACTERISTICS: CYLD cutaneous syndrome (CCS) typically manifests in the second or third decade with the appearance of multiple skin tumors including cylindromas, spiradenomas, trichoepitheliomas, and rarely, membranous basal cell adenoma of the salivary …
CLINICAL CHARACTERISTICS: CYLD cutaneous syndrome (CCS) typically manifests in the second or third decade with the appearance of mult …
Loss of CYLD might be associated with development of salivary gland tumors.
Fukuda M, Hiroi M, Suzuki S, Ohmori Y, Sakashita H. Fukuda M, et al. Oncol Rep. 2008 Jun;19(6):1421-7. Oncol Rep. 2008. PMID: 18497946
We demonstrated previously that human salivary gland tumor (SGT) cell line, HSG spontaneously expresses CYLD and also found that adenoid cystic carcinoma (ACC) arising from the hard palate was distinctly positive for CYLD, immunohistochemically. Howeve …
We demonstrated previously that human salivary gland tumor (SGT) cell line, HSG spontaneously expresses CYLD and also f …
Frequent and differential mutations of the CYLD gene in basal cell salivary neoplasms: linkage to tumor development and progression.
Rito M, Mitani Y, Bell D, Mariano FV, Almalki ST, Pytynia KB, Fonseca I, El-Naggar AK. Rito M, et al. Mod Pathol. 2018 Jul;31(7):1064-1072. doi: 10.1038/s41379-018-0018-6. Epub 2018 Feb 20. Mod Pathol. 2018. PMID: 29463883 Free article.
These neoplasms also share considerable phenotypic resemblance and co-exist with certain dermal adnexal tumors harboring the CYLD gene mutations inferring common genetic association. We sequenced the CYLD gene in both basal cell adenomas and adenocarcinomas and corr …
These neoplasms also share considerable phenotypic resemblance and co-exist with certain dermal adnexal tumors harboring the CYLD gen …
Expression of CYLD, NF-kappaB and NF-kappaB-related factors in salivary gland tumors.
Fukuda M, Fukuda F, Horiuchi Y, Oku Y, Suzuki S, Kusama K, Sakashita H. Fukuda M, et al. In Vivo. 2006 Jul-Aug;20(4):467-72. In Vivo. 2006. PMID: 16900776 Free article.
CYLD has deubiquitinating enzyme activity and inhibits the activation of transcription factor NF-kappaB. Therefore, loss of CYLD function correlates with tumorigenesis. Expression of CYLD has been detected in various organs, but its expression in salivary …
CYLD has deubiquitinating enzyme activity and inhibits the activation of transcription factor NF-kappaB. Therefore, loss of CYLD …
CTNNB1 mutations in basal cell adenoma of the salivary gland.
Lee YH, Huang WC, Hsieh MS. Lee YH, et al. J Formos Med Assoc. 2018 Oct;117(10):894-901. doi: 10.1016/j.jfma.2017.11.011. Epub 2017 Dec 7. J Formos Med Assoc. 2018. PMID: 29224720 Free article.
BACKGROUND/PURPOSE: Basal cell adenoma (BCA) and basal cell adenocarcinoma (BCAC) are uncommon salivary gland tumors comprising proliferation of basaloid cells. Nuclear beta-catenin expression and mutations in its encoding gene (CTNNB1) are reported to be specific t …
BACKGROUND/PURPOSE: Basal cell adenoma (BCA) and basal cell adenocarcinoma (BCAC) are uncommon salivary gland tumors comprisin …
Distinctive Patterns of CTNNB1 (beta-Catenin) Alterations in Salivary Gland Basal Cell Adenoma and Basal Cell Adenocarcinoma.
Jo VY, Sholl LM, Krane JF. Jo VY, et al. Am J Surg Pathol. 2016 Aug;40(8):1143-50. doi: 10.1097/PAS.0000000000000669. Am J Surg Pathol. 2016. PMID: 27259009
Salivary gland basaloid neoplasms are diagnostically challenging. Limited publications report that some basal cell adenomas harbor CTNNB1 mutations, and nuclear beta-catenin expression is prevalent. ...Basal cell adenocarcinoma showed a more complex genomic profile, …
Salivary gland basaloid neoplasms are diagnostically challenging. Limited publications report that some basal cell adenomas ha …
PLAG1 and CYLD do not play a role in the tumorigenesis of adenoid cystic carcinoma.
Daa T, Nakamura I, Yada N, Arakane S, Nishida H, Kashima K, Suzuki M, Yokoyama S. Daa T, et al. Mol Med Rep. 2013 Apr;7(4):1086-90. doi: 10.3892/mmr.2013.1311. Epub 2013 Feb 6. Mol Med Rep. 2013. PMID: 23404581
The pleiomorphic adenoma gene 1 (PLAG1) gene is activated in a subset of pleomorphic adenomas of the salivary gland by gene fusion. Germ-line mutation in cylindromatosis (CYLD), a tumor suppressor gene, causes familial cylindromatosis and Brook-Spiegler syndr …
The pleiomorphic adenoma gene 1 (PLAG1) gene is activated in a subset of pleomorphic adenomas of the salivary gland by gene fu …
Brooke-Spiegler Syndrome and Phenotypic Variants: An Update.
Kazakov DV. Kazakov DV. Head Neck Pathol. 2016 Jun;10(2):125-30. doi: 10.1007/s12105-016-0705-x. Epub 2016 Mar 14. Head Neck Pathol. 2016. PMID: 26971504 Free PMC article. Review.
Malignant tumors arise in association with preexisting benign cutaneous neoplasms in about 5-10% of the patients . Apart from the skin, major and minor salivary glands have been rarely involved in BSS patients. Extremely rare is the occurrence of breast tumors (cyli …
Malignant tumors arise in association with preexisting benign cutaneous neoplasms in about 5-10% of the patients . Apart from the skin, majo …
Brooke-Spiegler syndrome presenting multiple concurrent cutaneous and parotid gland neoplasms: cytologic findings on fine-needle sample and description of a novel mutation of the CYLD gene.
Malzone MG, Campanile AC, Losito NS, Longo F, Perri F, Caponigro F, Schiavone C, Ionna F, Maiello F, Martinuzzi C, Nasti S, Botti G, Fulciniti F. Malzone MG, et al. Diagn Cytopathol. 2015 Aug;43(8):654-8. doi: 10.1002/dc.23275. Epub 2015 May 21. Diagn Cytopathol. 2015. PMID: 25995191
Multiple dermal cylindromas and membranous basal cell adenoma of parotid gland in a 67-year-old woman with Brooke-Spiegler syndrome (BSS) were examined by fine-needle cytology. ...CYLD gene showed a novel germline splice acceptor site mutation (c.2042-1G>C) with …
Multiple dermal cylindromas and membranous basal cell adenoma of parotid gland in a 67-year-old woman with Brooke-Spiegler syndrome ( …
22 results